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UID:2026091612030220150212T00000020150212T0000006aa9dcb61b9e0@uic.edu
CATEGORIES:MEETING
STATUS:TENTATIVE
DTSTAMP:20190617T022455
DTSTART:20150212T000000
DTEND:20150212T000000
SUMMARY:Efie Kokkoli, University of Minnesota
DESCRIPTION:Design of Peptide- and Aptamer-Amphiphiles for Targeted Drug Delivery and Tissue Engineering  Self-assembly of biological molecules is an attractive method for engineering supramolecular biomaterials for different applications. I will discuss the design of a fibronectin-mimetic peptide-amphiphile and how we have used it to functionalize nanoparticles (stealth liposomes and polymersomes) for the targeted delivery of different therapeutics, both in vitro and in vivo. This fibronectin-mimetic peptide has also been used in our lab for the design of hydrogels, as tissue engineering scaffolds, for the entrapment of cells. Finally, I will introduce a new class of amphiphilic molecules, DNA-amphiphiles, that depending on the building blocks used for their design they can self-assemble into supramolecular nanostructures with non-spherical geometries, which is an area of great interest in DNA nanotechnology. | Event post: https://che.uic.edu/events?page_id=1110
LOCATION:230 CEB 810 S. Clinton Street  Chicago IL 60612
CLASS:PRIVATE
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