Sep 17 2015

Ankit Mehta, University of Illinois at Chicago

September 17, 2015

11:00 AM - 12:00 PM


218 CEB


810 S. Clinton Street, Chicago, IL 60612

Drug Delivery for Brain Tumors: An Engineering and Surgical Challenge

Hosted by: Vikas Berry

With emerging drug delivery technologies becoming accessible, more options are expected to become available to patients with glioblastoma (GBM) in the near future. It is important for clinicians and engineers to be familiar with the underlying mechanisms and limitations of intratumoral drug delivery, and direction of recent research efforts. Tumor-adjacent brain is an extremely complex living matrix that creates challenges with normal tissue intertwining with tumor cells. For convection-enhanced delivery (CED), the role of tissue anisotropy for better predicting the biodistribution of the infusate has recently been studied. Computational predictive methods are now available to better plan CED therapy. Catheter design and placement—in addition to the agent being used—are critical components of any protocol. Intratumoral therapies for GBM require a knowledge of anatomic and physiological perspectives, agents (immunotoxins), and new developments such as nanotechnology.


UIC Chemical Engineering

Date posted

Jun 17, 2019

Date updated

Jun 17, 2019